If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Do not store in the bathroom. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. This medication may interfere with certain laboratory tests (including cholesterol levels), possibly causing false test results. Natural Medicines. It works and leaves the body quickly, so it needs to be taken twice a day. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Tachjian A, et al. All rights reserved. It will not treat an angina attack that has already begun. You may report side effects to the FDA at 1-800-FDA-1088. Prescription and OTC The .gov means its official. Registered in England and Wales. It will not treat an angina attack that has already begun. Ask your pharmacist any questions you have about refilling your prescription. This medication belongs to a class of drugs known as. Your doctor may recommend treating headaches with an over-the-counter pain reliever (such as acetaminophen, aspirin). Is not subject to the Controlled Substances Act. Although unlikely, when this medication is used for a long time, it may not work as well and may require different dosing. American Society of Health-System Pharmacists, Inc. Disclaimer, U.S. Department of Health and Human Services. Are you looking for information on isosorbide dinitrate (Isordil) instead? Isosorbide mononitrate (Monoket) may interact with certain medications or supplements. Do not keep out-of-date or unwanted medicines. Take care, thanks. All rights reserved. Herbal supplements can strongly affect the body. Severe postural hypotension with light-headedness and dizziness is frequently observed after the consumption of alcohol. Always consult your healthcare provider. Things to remember when you fill your prescription. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Alternative cancer treatments: 11 options to consider. . Natural Medicines. This medicine is a white, round, scored, tablet imprinted with "KU 107" and "20". 8600 Rockville Pike The tablet usually is taken two or three times daily. Normal ecg doesn't rule out heart disease. tell your doctor and pharmacist if you are allergic to isosorbide; nitroglycerin tablets, patches, or ointment; any other medications, or any of the ingredients in isosorbide tablets, extended-release tablets, or extended-release capsules. Journals of the American College of Cardiology. Natural Medicines. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. The body tends to develop a tolerance (decreased sensitivity) to ISMN when it is used continuously over 24 hours. Sept. 26, 2022. https://naturalmedicines.therapeuticresearch.com. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. This is not a complete list of possible side effects. Laboratory and/or medical tests (such as blood pressure) should be performed periodically to monitor your progress or check for side effects. Patient does not provide medical advice, diagnosis or treatment. (1) Starting on a low dosage was associated with a reduced frequency and severity of headache and did not notably influence the beneficial effect on angina pectoris. Valerian: A safe and effective herbal sleep aid? Isosorbide is in a class of medications called vasodilators. The extended-release capsule usually is taken once daily. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Swallow the tablet/capsule whole - do not chew or crush it before you swallow. Licorice. This product may contain inactive ingredients, which can cause allergic reactions or other problems. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. amlodipine, lisinopril, aspirin, metoprolol, furosemide, carvedilol, propranolol, spironolactone, atenolol, diltiazem. The longer you take isosorbide mononitrate, the more your body can become used to it (called tolerance), and then it can have less of an effect. The IR version can help treat and prevent angina. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or to 30 mg 5-ISMN od for one week followed by 60 mg 5-ISMN od for one week. Daily headaches are a common side effect. Many herbal supplements can interact with prescription drugs. Moderately clinically significant. You can consult me online for homeopathic treatment. Properly discard this product when it is expired or no longer needed. For these reasons, before you start taking isosorbide mononitrate it is important that your doctor knows: Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. We comply with the HONcode standard for trustworthy health information. If you have an eye condition called glaucoma. Never take extra doses or stop taking it suddenly unless your provider tells you to do so. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). Seek alternatives to the CYP3A4 substrate when possible. Also, it is not intended to be taken just before physical activities (such as exercise or sexual intercourse) to prevent chest pain. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Natural remedies for depression: Are they effective? Both versions of isosorbide mononitrate (Monoket) contain the same active ingredient. https://naturalmedicines.therapeuticresearch.com. Along with its needed effects, a medicine may cause some unwanted effects. . Some of the common derivatives include isosorbide dinitrate and isosorbide mononitrate, which are . Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. May also be prescribed off label for Esophageal Spasm. Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. It relaxes blood vessels in your body (causing them to widen) and this reduces the strain on your heart, making it easier for your heart to pump blood around your body. Vascular dilatation can precipitate venous pooling with decreased return to the heart, hypotension and reflex tachycardia. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Enter other medications to view a detailed report. Isosorbide mononitrate (Monoket) is available as a generic medication and may be significantly cheaper compared to the brand version. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Profen and Metoclopramide drug interaction, Metoclopramide and Nitrostat drug interaction, Metoclopramide and Alfentanil drug interaction, Risperdal and Metoclopramide drug interaction. My EKG showed Assess your symptoms online with our free symptom checker. View more, Nitroglycerin dilates veins, relieving chest pain and lowering blood pressure. Higher than recommend dosage of sublingual isosorbide dinitrate for treating angina pectoris: a case report and review of the literature. Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. Mehta D. Herbal & dietary supplements. Check with your doctor immediately if any of the following side effects occur: burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, fast, slow, irregular, pounding, or racing heartbeat or pulse, itching, pain, redness, or swelling on the leg, numbness or tingling in the hands, feet, or lips, pain or discomfort in the arms, jaw, back, or neck, pain, tension, and weakness upon walking that subsides during periods of rest, shakiness in the legs, arms, hands, or feet, swelling of the face, fingers, feet, or lower legs, trembling or shaking of the hands or feet, vomiting of blood or material that looks like coffee grounds, Bluish-colored lips, fingernails, or palms. In the US - Call your doctor for medical advice about side effects. Alcohol, including beer, wine, and spirits, does raise your blood pressure if its consumed in excess. If you have any questions about this medicine ask your pharmacist. Which drugs or supplements interact with isosorbide mononitrate? Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Isosorbide mononitrate has an average rating of Herbal supplements and heart medicines may not mix, Your blood pressure, if you also take a drug to treat high blood pressure, Beta blockers, such as atenolol (Tenormin), nadolol (Corgard) or propranolol (Inderal LA, Innopran XL), Calcium channel blockers, such as diltiazem, nifedipine (Procardia) and verapamil (Calan SR, Verelan), Nitrates, such as nitroglycerin (Nitrostat, Nitro-Dur, others) and isosorbide (Isordil, Bidil), Statins, such as atorvastatin (Lipitor), lovastatin (Altoprev) and rosuvastatin (Crestor), Anti-rejection medicine, also called immunosuppressant medicine, such as cyclosporine (Gengraf, Neoral, Sandimmune). This is called tolerance, and it cannot be fixed by raising the dose of the medication. All rights reserved. View World Anti-Doping Agency classifications, Prevention of Thromboembolism in Atrial Fibrillation, Prosthetic Heart Valves - Thrombosis Prophylaxis, Prosthetic Heart Valves - Mechanical Valves - Thrombosis Prophylaxis, Revascularization Procedures - Prophylaxis. Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. In: Current Medical Diagnosis & Treatment 2022. We don't support your browser. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. The information on this page is written and peer reviewed by qualified clinicians. You may report side effects to Health Canada at 1-866-234-2345. Using this medicine with any of the following medicines is not recommended. Store it at room temperature and away from excess heat and moisture (not in the bathroom). isosorbide mononitrate (Rx) Brand and Other Names: Imdur, Monoket, more. Review/update the The short-acting tablet is usually taken as 10 mg to 40 mg by mouth 2 or 3 times daily with at least a 14 hour period of time per day where you don't take any doses. Your doctor may tell you to take a pain reliever to treat your headaches. Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Consult your doctor before breast-feeding. Important information about all medicines, Notes on Isosorbide mononitrate dose and side-effects info, https://patient.info/medicine/isosorbide-mononitrate-elantan-imdur-isotard-monomax-tardisc-xismox, Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets, Carmil XL; Chemydur XL; Elantan LA; Imdur; Isib XL; Ismo; Isodur XL; Isotard XL; Modisal XL; Monomax SR; Monomil XL; Nyzamac SR; Relosorb XL; Tardisc XL; Trangina XL; Xismox XL; Zemon XL, Tablets, modified-release (longer-acting) tablets, and modified-release (longer-acting) capsules, Ask your doctor or pharmacist to recommend a suitable painkiller. Some products that may interact with this drug include: drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), riociguat. An official website of the United States government. Herbal medications in cardiovascular medicine. Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets; Merus Labs Luxco S.a.R.L, The electronic Medicines Compendium. Contact your doctor immediately if you experience any of the following: The following side effects may get better over time as your body gets used to the medication. Let your provider know if they are excessive. FOIA If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. coma (loss of consciousness for a period of time). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Evening primrose. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. WebMD does not provide medical advice, diagnosis or treatment. Accessed Sept. 7, 2022. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Instead, the best way to dispose of your medication is through a medicine take-back program. I would rather take the chance of a heart attack than have no quality of life. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Isosorbide may cause other side effects. URL of this page: https://medlineplus.gov/druginfo/meds/a682348.html. Prices for isosorbide mononitrate (Monoket) start at just $29.86 with a GoodRx coupon. Take them to your local pharmacy which will dispose of them for you. It works by . It might help to keep the room cool and use a fan. This is so your doctor can check on your progress. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. Before A single copy of these materials may be reprinted for noncommercial personal use only. Modified-release nitrate preparations: use a once-daily dose to maintain a nitrate-low period and thus minimize tolerance. This document does not contain all possible drug interactions. Would you like email updates of new search results? Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Does Isosorbide Mononitrate interact with other drugs you are taking? Isosorbide controls chest pain but does not cure coronary artery disease. Some don't work well with prescription medicines. The authors assessed the occurrence of angina pectoris and headache by diary cards while taking into account the number of isosorbide dinitrate sublingual puffs and paracetamole tablets required. AHFS Patient Medication Information. Learn to reduce stress through mindful living. Isosorbide mononitrate (Monoket) can cause your blood pressure to drop somewhat. Herbal supplements can strongly affect the body. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 2023 Lybrate, Inc. All rights reserved. Mehta D. Botanical medicines. Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Minimally clinically significant. Isosorbide mononitrate vs. Amlodipine besylate, Isosorbide mononitrate vs. Bisoprolol fumarate, Isosorbide mononitrate vs. Diltiazem hydrochloride, Isosorbide mononitrate vs. Isosorbide dinitrate, Isosorbide mononitrate vs. Metoprolol succinate, Isosorbide mononitrate vs. Metoprolol tartrate, Isosorbide mononitrate vs. Nitrolingual pumpspray, Isosorbide mononitrate and Aspirin (7,880 reports), Isosorbide mononitrate and Furosemide (6,020 reports), Isosorbide mononitrate and Amlodipine (3,554 reports), Isosorbide mononitrate and Simvastatin (3,508 reports), Isosorbide mononitrate and Omeprazole (3,422 reports), Isosorbide mononitrate and Lisinopril (3,099 reports), Isosorbide mononitrate and Metformin (2,822 reports), Isosorbide mononitrate and Carvedilol (2,589 reports), Isosorbide mononitrate and Clopidogrel (2,524 reports), Isosorbide mononitrate and Acetylsalicylic acid (2,355 reports). Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. Be sure to talk to your health care provider before you take any herbal supplements if you take prescription medicines. Isosorbide tablets are also used with other medications to treat heart failure. A randomized, double-blind, cross-over study. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Call your doctor if you have any unusual problems while you are taking this medication. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain ( angina ), heart failure and esophageal spasms. Do not take a double dose to make up for a missed one. Copyright, 2023. Read our editorial policy. isosorbide mononitrate, along with This medication belongs to a class of drugs known as nitrates. Conclusions: It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Each day, take the first dose when you wake up, then take the second dose 7 hours later. Dehydration in Buspar, how severe and when it was recovered? Nitrate-Induced Headache in Patients with Stable Angina Pectoris: Beneficial Effect of Starting on a Low Dosage. Isosorbide mononitrate belongs to the group of medicines called nitrates. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking isosorbide. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. Dated October 2016. What should I know regarding pregnancy, nursing and administering Isosorbide Mononitrate to children or the elderly? 1994 Jan;15(1):108-13. doi: 10.1093/oxfordjournals.eurheartj.a060361. The extended-release tablet usually is taken once daily in the morning. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. However, you should not flush this medication down the toilet. Garlic. Browse all drugs on eHealthMe. This content does not have an Arabic version. Call your doctor for medical advice about side effects. This form of skin cancer is mostly caused by PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care, MBBS, Master in Healthcare Administration, Diploma in Occupational Health, What are the uses of Isosorbide Mononitrate. It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen. This site complies with the HONcode standard for trustworthy health information: verify here. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. During pregnancy, this medication should be used only when clearly needed. Accessed Sept. 7, 2022. Using this medicine with any of the following medicines is not recommended. Integrative medicine (complementary and alternative medicine). Therefore, oral nitrates should not be used by patients who are sensitive to the effects of hypotension, such as those with pre-existing hypotension, shock, vascular collapse or significant cerebrovascular disease, significant anaemia or hypothyroidism. Isosorbide mononitrate (Monoket) works slowly to help prevent chest pain. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. Accessed Sept. 7, 2022. Isosorbide mononitrate is very similar to isosorbide dinitrate. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, List Isosorbide Mononitrate side effects by likelihood and severity. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Other medications may be prescribed by your doctor for these conditions. Murray MT. Available for Android and iOS devices. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Egton Medical Information Systems Limited. Do infrared saunas have any health benefits? Does Alcohol Raise Your Blood Pressure? It is important to take the drug at the same times each day. Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Nitrates (eg, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin). Isosorbide mononitrate Aspirin Prescription only Prescribed for Angina Pectoris Prophylaxis, Heart Failure. This survey is being conducted by the WebMD marketing sciences department. Compare a few possible alternatives below. government site. Your doctor will probably tell you not to take isosorbide if you are taking one of these medications. See the full pregnancy warnings document. If you become pregnant while taking isosorbide, call your doctor. Dated August 2017. Some brands of isosorbide mononitrate tablets should be taken two or three times a day. Medicines containing Isosorbide Mononitrate. Trapidil is as effective as isosorbide-dinitrate for treating stable angina pectoris: a multinational, multicenter, double-blind, randomized study. This is called a medicine interaction. As precautionary measure, it is preferable to avoid the use of isosorbide mononitrate during pregnancy. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location one that is up and away and out of their sight and reach. For haemoglobin formation vit. Diabetes treatment: Can cinnamon lower blood sugar? isosorbide mononitrate prices. The Swedish Multicentre Group. View all On the other hand, the ER version can only help prevent angina. To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up. Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks ( chest pain ). Isosorbide mononitrate works in two ways. Consult your pharmacist or local waste disposal company. See also: nitroglycerin side effects in more detail. Accessed Sept. 7, 2022. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Data were assessed for carryover and time effects. You need to take it every day in order for it to work. Accessed Sept. 7, 2022. As precautionary measure, breast-feeding should be discontinued during treatment with isosorbide mononitrate. Isosorbide mononitrate (Monoket) is available as both a immediate-release (IR, short-acting) and extended-release (ER, long-acting) tablet. 7.6 out of 10 from a total of The most common side-effect is headache. About one-half of adults in the United States say they have used one or more supplements in the past 30 days. Take your next dose at the regular time. Do not stop taking isosorbide without talking to your doctor. May also be prescribed off label for Esophageal Spasm. Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, isosorbide mononitrate consumer information. This medicine is available only with your doctor's prescription. Some people feel dizzy or fall when changing positions, such as going from sitting to standing. The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. Even if the medication is working, you may experience some unwanted side effects. Do not drink alcohol while taking View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Isosorbide mononitrate helps to prevent angina chest pain from developing. Consult your doctor for more details. This is a condition where the heart does not beat as efficiently as it should. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Try to keep your regular appointments with your doctor. Alcohol will increase the risk of you experiencing side-effects such as feeling dizzy and light-headed. Reduction of blood-nitrate concentrations to low levels for 4 to 12 hours each day usually maintains effectiveness in such patients. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or . Treatment and prognosis of heart failure with preserved ejection . Making any changes without doctor's advice can be dangerous. It took me a few weeks to adapt to it, but the effect on preventing chest pain was dramatic. Is isosorbide mononitrate (Monoket) the same as nitroglycerin (Nitrostat)? Click here for an email preview. Limit alcoholic beverages. Isosorbide-5-mononitrate ISMN usually begins acting within 30 minutes and its effects last six to eight hours. AskMayoExpert. It might help to take isosorbide mononitrate and dinitrate after meals. daily and increasing to 40 mg three times daily as necessary, given at 8 AM, 1 PM, and 6 PM), isosorbide mononitrate (starting at 30 mg/day in the morning and increasing to 120 mg/day as necessary), or a transdermal. Does isosorbide mononitrate (Monoket) lower blood pressure?
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